Simulated microgravity activates apoptosis and NF-κB in mice testis
نویسندگان
چکیده
منابع مشابه
Simulated microgravity decreases apoptosis in fetal fibroblasts.
Space travel is a major challenge for human beings. Especially, the mechanisms through which space conditions might alter animal development have been questioned for a long time. The two major physical stress factors that are of relevance in this context are space radiation and weightlessness. While it has been extensively shown that high doses of ionizing radiation induce deleterious effects o...
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The transcription factor NF-kB has for some years been recognized to be a central mediator of the gene expression induced in cells by pathogens or inflammatory cytokines, and is known to play an important role in development of the immune system [1]. To the list of NF-kB’s biological activities can now be added a role in countering the induction of apoptosis (or programmed cell death) by the cy...
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ژورنال
عنوان ژورنال: Molecular and Cellular Biochemistry
سال: 2008
ISSN: 0300-8177,1573-4919
DOI: 10.1007/s11010-008-9743-3